Generation of Rate-Tuned Pacemaker Organoids from Human Pluripotent Stem Cells

Misato Koakutsu, cardiac research fellow at the Johns Hopkins University School of Medicine, discusses her abstract involving generated sinoatrial node organoids (SANOs) from human induced pluripotent stem cells (hiPSCs)-derived atrial myocytes and proepicardial cells. This was the topic of her presentation during the American Heart Association Scientific Sessions 2023. The research team aims to provide an alternative treatment for pacing device-dependent heart rhythm problems using stem cell-based biological pacemakers.

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Johns Hopkins Medicine