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Answer ALS: A Longitudinal Clinical and Biological Approach to Studying the Disease

Johns Hopkins neurologist Jeffrey Rothstein describes the personalized medicine initiative, Answer ALS, which gathered data points — both clinical and biological in nature.

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Autophagy and Neurons — Targeting Protein Quality Control for Modifying Proteostasis and Discovering Therapeutic Targets for Neurodegenerative Diseases

Johns Hopkins neurologist Jason Chua recaps a recent presentation about the discovery of a novel mechanism of modulating autophagy, a conserved pathway of protein quality control.

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Cognitive Disruption After Minor Stroke Is Due to Network Disruption

Johns Hopkins neurologist Elisabeth Marsh discusses the under recognized deficits of stroke recovery and the work she is doing to understand the brain pathophysiology of those deficits, as well as possible therapeutic targets that to help with recovery.

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Johns Hopkins Researchers Identify a Potential Window for Treating ALS

Johns Hopkins Medicine researchers have found a possible window of opportunity during ALS treatment to target astrocyte abnormalities — a subtype of cells in the central nervous system that provide a structure to metabolically support ...

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Researchers Aim to Improve Lifespan and Quality of Life for Patients with Brain Tumors

Johns Hopkins neurosurgeon-scientists test a gamut of new therapeutic approaches — such as using bioengineered cancer cells to produce neoantigens that activate immune response. They simultaneously develop new tools and techniques to improve quality of life.

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Leading-Edge Approaches and Research to Improve Surgical Spine Treatments and Outcomes

Spine neurosurgeons use technologies co-developed by faculty members to advance patient care. Plus, a first-of-its-kind lab creates a new class of implantable, wearable medical devices to aid those with spinal cord injuries.