Johns Hopkins has an essential role in the innovation of heart research. Pediatric heart surgeon Danielle Gottlieb Sen discusses the two major areas of her research: the genetic origins of congenital heart disease and engineering involving monitoring devices for babies and children with this illness.
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hopkinschildrens.org/heart-research. My name is Danielle Gottlieb SEn and I'm a pediatric heart surgeon and I'm director of pediatric cardiac surgery research at johns Hopkins Children's Center. Well, my research is considered translational and it involves two major areas of focus. The first relates to the origins of congenital heart disease and we study normal embryo logic development and also study human disease tissue issues in order to get human disease tissues. We've created a human cardiac surgery by repository, which means that families and patients are able to join us in trying to understand what the origins of some congenital heart diseases are in which parts of the left side of the heart and circulation are small. We also worked with with mouse models of normal development. The secondary of focus of my research is centered in engineering and involves medical device development, specifically monitoring devices for monitoring babies and Children with congenital heart disease. My original motivation for research and congenital heart surgery had to do with surgical cure and trying to mitigate the most severe forms of disease that we see. The monitoring device technology focus came from wanting to make care better for the patients and families we take care of well as a surgeon, I have the privilege of taking care of patients and families one at a time and also in a very personal way and the focus of my research. The idea of research has to do with with touching broader groups of patients. So to me, success and research would be contributing to the quantity and quality of life that our patients have but on a bigger scale