Experts from Johns Hopkins Children’s Center participated in various sessions and presentations during the 2023 Pediatric Academic Societies Meeting. In this video, Sanjana Boyapalli, research program coordinator for pediatric nephrology, discusses her team’s research on how socioeconomic status (SES) is associated with hypertension and heart disease risks. This study also explores how disease risks are elevated during childhood because of SES. Exploring this topic would assist with developing proactive measures earlier in life to slow chronic disease progression.
Hi, my name is Sanjana Boy Poli and I'm a research coordinator here at the Johns Hopkins Department of Pediatric Nephrology. The study that we presented at the Pediatric Academic Societies conference is the Association of Socioeconomic Status and cardiovascular disease Risk factors in youth. There is a lot of existing literature that indicates that childhood socioeconomic status or S CS is related to cardiovascular disease risk in adulthood, which makes sense because cardiovascular diseases tend to be chronic illnesses that develop over time. However, there's not much research on whether disease risk is already elevated in childhood itself with respect to socio-economic status. It's important that we understand this so that we can develop and employ proactive measures more strategically earlier in life to prevent or slow down chronic disease progression. So, my team and I looked at the independent association of neighborhood S E S with blood pressure, blood pressure, variability and arterial stiffness in youth. The S CS metric that we used was the area deprivation index or AD I which is based on census data related to the patient's residential address and high AD I indicates higher deprivation and thus lower S E S ultimately of the 78 Children whose data we analyzed, we found no differences in arterial stiffness between groups. However, after adjusting for both age and sex, low S E S and high ad I were associated with increased systolic blood pressure variability and high ad I was associated with the manual systolic blood pressure index. Interestingly, these relationships lost their significance after adjusting for obesity, which may indicate that obesity prevention and treatment measures are still effective interventions in these populations and are something we should explore further. Thanks so much for watching.