Chapters Transcript Video Andrea Fava, MD - Urine Proteomics and Single Cell Transcriptomics Identify IL-16 as a Biomarker for Lupus Nephritis Andrea Fava discusses the use of urine samples to detect a patient’s kidney disease progression. Orson is titled Urine Proteomics and Single Cell Transcript Comics identify into looking 16 as a biomarker for Lupus and Fridays. We have measured 1000 different substances in the urine off patients with kidney Lucas, and we found a new substance called into looking 16 that can predict the patients that have more aggressive the kidney disease and Lucas right now, patients who we suspect have kidney Lucas. In order to diagnose that, we have to do a kidney biopsy, which is a procedure, and it is invasive. So now this sort of study can help designing and developing what we call the liquid biopsy, which means that we could use a sample of urine, which is non invasive, in order to diagnose patients with aggressive disease. Also with it additional studies looking inside the kidneys of these patients. And we found that this substance into looking 16 it is one of the main, um, mediator is is one of the main products that are made in the kidneys, a patient with Lupus, and so that is probably a new target for treatment, which means that if more research confirms what we are finding, a new drug may be coming to target this molecule. This substance Created by Related Presenters Andrea Fava, MD Assistant Professor of Medicine, Division of Rheumatology View full profile