Urology Speaks: Ecology Meets Cancer Biology: Defining the Keystone Cancer Cell Species to Develop a Cure

There are two major challenges to cancer patient survivorship: metastasis and therapy resistance. By applying an ecological framework to study how individual cells move and respond to stress, we have identified a Keystone Cancer Cell that underlies both processes. Dr. Amend presents background information on the Keystone Cancer Cell, and reviews our current efforts to design treatment strategies that target the unique vulnerabilities of these cells, a theory called evolutionary double bind.

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Johns Hopkins Medicine

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Sarah Amend, PhD

Sarah Amend, PhD

Assistant Professor of Urology

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