Pediatric pulmonologist Brianna Aoyama discusses her latest research in bronchopulmonary dysplasia (BPD). The lungs of premature infants with this diagnosis improve with growth and age. However, a major complication of BPD is the development of chronic lung disease. The goal of the research is to advance the care patients receive after this diagnosis, and improve lung health for a lifetime.
Hi, my name is Brianna Palyama and I'm an assistant professor of pediatrics in the division of pediatric pulmonary medicine. I'm excited to talk with you today about our work in understanding the epidemiology and long term outcomes of infants and Children with broncho pulmonary dysplasia, or BPD. Each year, an estimated 10% of the four million infants born in the us are born prematurely or less than 37 weeks. Gestation. BPD is the major respiratory complication of prematurity affecting Alveoli, airways and vasculature within the lungs. Despite advances in neonatal care and technology, including gentler ventilation strategies, exogenous surfactant parental nutrition and the widespread use of prenatal steroids. The incidence of BPD has remained unchanged for the past several decades, affecting up to 50,000 infants annually in the us. For many Children with BpD, their respiratory symptoms improve with age and growth. However, many survivors of BpD have chronic lung disease characterized by airflow obstruction and intermittent pulmonary exacerbations leading to treatment with antibiotics and steroids. 80 evaluation and admissions to the hospital long term lung function trajectories as measured by F. E. V. One can be lower in Children and adults with a history of BpD. Most recently, our research has described the increased risk of mortality appreciated in these Children. The role of socioeconomic status as a potential barrier to subspecialty. Follow up the association of somatic growth and nutrition and lung growth and function in early childhood and the use of force to salam a tree or fo ti. A novel of lung function that can be employed in early childhood before Children can reliably perform spectrometry are standard measure of lung function. Ongoing work in many areas of pediatrics has highlighted the effects of early life events on adult outcomes. While premature birth can have lifelong consequences. Preterm Children are an understudied group after discharge from the NICU. We hope that our ongoing work will provide novel insight into some of the early life issues that these Children and their families face and improve the care that they receive to hopefully improve lung health for a lifetime. Thank you.