Gastroenterology Articles

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Research Shows Promise for Personalized Medicine in Crohn’s Disease

Recent study suggests potential new treatments for subset of patients carrying genetic mutation.

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Preventing Pancreatitis After ERCP

Johns Hopkins physician-researchers aim to make a key procedure safer.

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Toward Ending Viral Hepatitis in Vietnam

Johns Hopkins hepatologists Doan Dao and James Hamilton, along with philanthropists Mai and Volker Dolch, aim to eradicate this primary driver of deadly liver cancer by 2030.

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Johns Hopkins Study Reveals Racial and Socioeconomic Disparities in Liver Transplant

Researchers demonstrate that patients from underrepresented populations living in low-socioeconomic neighborhoods are at significant risk of not receiving the care they require.

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Johns Hopkins Hepatologists Detect Liver Cancer in Urine Test

Researchers show that screening urine for ctDNA as part of a two-stage test increases detection sensitivity from 40% to 77% in early-stage liver cancer, and from 62% to 92% in the very early stage of disease.

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Study Reveals High Prevalence of Alcohol, Opioid Use Among Patients with Crohn’s Disease in U.S.

Newly diagnosed people with Crohn’s disease (CD) in the United States are more likely to experience drug and alcohol use compared with the general population, according to a recent study led by Johns Hopkins Medicine researchers. The study, ...

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Johns Hopkins Among Few in U.S. to Offer Early Liver Transplants for Patients with Alcohol-Associated Liver Disease

New research opens window into understanding the needs of patients after the procedure.

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Gastroenterologist Develops Gel to Stop Bleeding After Precancerous Polyp Removal

Venkata Akshintala leads a team of pharmacologists, biomedical engineers and mechanical engineers to create a gel that uses epinephrine nanoparticles to stop bleeding following a procedure.

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Nanofiber-Hydrogel Loaded with Stem Cells Shows Success Treating Severe Complication of Crohn’s Disease

In a new study using a rat model of Crohn’s disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown ...

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Should We Burn Barrett’s Esophagus? Or Should We Freeze It?

Clinical trials led by Johns Hopkins endoscopy specialists investigate cryotherapy approach to treat Barrett’s esophagus.

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Improving Pancreatic Cancer Survival Through Surveillance

Johns Hopkins-led study shows that for patients at high risk of developing disease, annual screening caught most pancreatic cancers in early, treatable stages.

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Johns Hopkins Gastroenterologist First in U.S. to Perform POEM+F—Recently Developed Approach for Achalasia and Acid Reflux

In 2012, Dr. Mouen Khashab, professor in the Division of Gastroenterology & Hepatology, pioneered peroral endoscopic myotomy (POEM) to treat esophageal achalasia – a disorder of the esophagus that makes swallowing difficult.

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Johns Hopkins Researchers Generate Lab-Grown Human Tissue Model for Food Tube Cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional “organoid” model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal ...

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DNA Shed from Colon Cancers into Bloodstream Guide Chemotherapy

A new research study showed that circulating tumor DNA (ctDNA) — genetic material shed from tumors into the bloodstream — can identify stage II colon cancer patients who can most benefit from chemotherapy following surgery and spare other ...

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Johns Hopkins Researcher Pioneers Artificial Intelligence to Identify and Count Nerve Cells in the Gut

Subhash Kulkarni and colleagues create open-source software with the potential to help unlock mysteries of the enteric nervous system.

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Johns Hopkins Gastroenterologist Founds Popular Global Discussion on IBD

Conceived and hosted by inflammatory bowel disease specialist Aline Charabaty, a weekly Twitter discussion known as @MondayNightIBD attracts as many as 700,000 viewers and includes some of the world’s top IBD physicians and scientists, ...

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Improved Imaging and Earlier Surgery Help Patients with Hereditary Pancreatic Cancer Live Longer

Researchers in the Johns Hopkins Division of Gastroenterology and Hepatology say the next step is earlier detection in those without familial risk.

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Johns Hopkins Oncologist Tests Vaccine for Pancreatic Cancer

The first-ever trials for an immunotherapy shot to prevent the lethal form of cancer are underway.

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Endoscopic Ultrasound Measures Pressure in Hepatic Portal Vein

Gaining access to the liver through the stomach, Olaya Brewer Gutierrez and her therapeutic endoscopy colleagues at Johns Hopkins use endoscopic ultrasound to obtain a direct reading of the pressure in the hepatic portal vein.

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A Rare, Stomach-Saving Endoscopic Procedure

When an otherwise healthy 69-year-old woman came to Johns Hopkins after a bout with gastroesophageal reflux disease, a routine endoscopy revealed a serious problem.

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Johns Hopkins Develops Tiny Machines That Deliver Medicine to the Intestines

Invented by biomedical engineer David Gracias and gastroenterologist Florin Selaru, “theragrippers” are devices that clamp onto intestinal mucosa and release medicine.

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Genetic Testing Reveals Important Clues in Unexplained Cases of Pancreatitis

For patients with recurrent acute or chronic pancreatitis, comprehensive genetic testing can help pinpoint the underlying cause of disease, avoiding potentially unnecessary tests and invasive treatments.

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Destigmatizing Liver Transplant for Patients with Alcohol Use Disorder

Johns Hopkins is one of the few centers in the United States that regularly transplants livers into patients with alcohol-related liver disease whose sobriety doesn’t reach six-month threshold.

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Making Anal Cancer Screening a Priority for High-Risk Patients

Ulrike Buchwald aims to detect anal lesions and dysplasia earlier in patients who are most vulnerable.

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Johns Hopkins Physicians Take on Hepatitis B Epidemic in Vietnam

New Center of Excellence will bring clinical care, research and education to Ho Chi Minh City.

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COVID-19 and IBD: New Survey Studies Underway at Johns Hopkins

Physicians and researchers in the Division of Gastroenterology and Hepatology seek to understand how COVID-19 affects patients with inflammatory bowel disease.

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Mentoring Women in Medicine

Director of Clinical Research Marcia “Mimi” Canto shares insights into her role as mentor in the Division of Gastroenterology and Hepatology.

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A Treatment Breakthrough for Pregnant Women with IBD

Johns Hopkins research suggests that women with IBD who discontinue infliximab early in pregnancy are more likely to flare, while continuation of the drug throughout term is not associated with poor outcomes for mothers or babies.

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Genetic Testing May Hold Promise in Predicting Pancreatic Cancer

Johns Hopkins research suggests that identification of particular genetic mutations could better predict risk and lead to improved survival rates.

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3D Tissue Models Offer Window into How Gut Cells Fight Infection

Nicholas Zachos and his team are the first to cultivate a primary human macrophage-enteroid system, which allows researchers to see, in real time, how the gut fights against infection.

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8 New Faculty Members Join Johns Hopkins Division of Gastroenterology and Hepatology

Meet the new team.

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Johns Hopkins Developing New Test for Esophageal Cancer

A Johns Hopkins gastroenterologist and a team of researchers use specific genetic biomarkers to detect dangerous changes in the cells that line the inside of the esophagus. 3D image shows concept model of esophageal cancer.

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Johns Hopkins Research Shows Potential for Cure for Polycystic Kidney Disease

Working both with mice and with 3D models of kidney cysts, genetics researcher Liudmila Cebotaru found that introducing a specific CFTR corrector slowed cystic growth.

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At Sibley Memorial Hospital in Washington, D.C. — A ‘Whole-Person’ Approach to IBD Care

Because the way patients experience IBD can vary widely, gastroenterologist Aline Charabaty prioritizes understanding the needs of each one before recommending treatment.

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Johns Hopkins Among First to Offer Flexible Robotic Endoscopy

Inside Tract Winter 2019

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Johns Hopkins Among First to Transplant HCV-Positive Livers Into HCV-Negative Patients

News & Publications January 8, 2019

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Hopkins Researchers Deliver Gene Therapy Directly to the Liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases.

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Post-Endoscopy Infection Rates Far Higher Than Expected at Ambulatory Surgery Centers

Centers with the highest volume of procedures had the lowest rates of post-endoscopic infection.

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Treating Gut Disease with Electrostimulation

Jiande Chen and team are using tiny electric shocks to reset the neural networks that regulate gut activity, with potential application for gastroparesis, functional bowel disorders and even diabetes.

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Rethinking Elimination Diets and FODMAPS: A Common-Sense Approach to IBS

Gastroenterologist Gerry Mullin says that draconian elimination diets often aren’t necessary. Plus, learn about his research into the microbiome’s role in weight loss.